NEET Biology Molecular Basis of Inheritance MCQs Set C

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MCQ for Full Syllabus Biology Molecular Basis of Inheritance

Full Syllabus Biology students should refer to the following multiple-choice questions with answers for Molecular Basis of Inheritance in Full Syllabus.

Molecular Basis of Inheritance MCQ Questions Full Syllabus Biology with Answers

 

 

Question: Haploid content of human DNA contains

  • a) 3.3 × 109 bp
  • b) 6.6 × 109 bp
  • c) 3.3 × 108 bp
  • d) 4.6 × 106 bp

Answer: 3.3 × 109 bp

 

Question: Which of the following nitrogenous bases are common for both RNA and DNA?

  • a) C, G, A
  • b) G, A, U
  • c) T, A, C
  • d) U, A, C

Answer: C, G, A

 

Question: Adjacent nucleotides in a polynucleotide chain are joined by

  • a) Phosphodiester bond
  • b) O-glycosidic bond
  • c) Hydrogen bond
  • d) N-glycosidic bond

Answer: Phosphodiester bond

 

Question: Sugars are attached to the pyrimidines by the formation of

  • a) N-glycosidic bond
  • b) Phosphoester bond
  • c) O-glycosidic bond
  • d) Hydrogen bond

Answer: N-glycosidic bond

 

Question: Cytidine is a

  • a) Nucleoside
  • b) Nucleotide
  • c) Nitrogen base
  • d) Common dinucleotide in DNA and RNA

Answer:  Nucleoside

 

Question: Which of the following process is related to reverse transcription?

  • a) RNA dependent DNA synthesis
  • b) RNA dependent polypeptide synthesis
  • c) DNA dependent DNA synthesis
  • d) DNA dependent RNA synthesis

Answer: RNA dependent DNA synthesis

 

Question: Which of the following structures are present in core particle of nucleosome?

  • a) Octamer of histone proteins
  • b) Non-histone proteins
  • c) 200 bp of DNA
  • d) Linker DNA

Answer: Octamer of histone proteins

 

Question: Packaging of DNA helix

  • a) Is more complex in eukaryotes than prokaryotes
  • b) Requires acidic proteins that help in coiling of DNA in prokaryotes
  • c) Occurs with the help of NHC proteins only
  • d) Involves polyamines in eukaryotes

Answer:  Is more complex in eukaryotes than prokaryotes

 

Question: Length of DNA in E. coli is

  • a) 1.36 mm
  • b) 1.36 m
  • c) 3.4 m
  • d) 2.2 m

Answer: 1.36 mm

 

Question: Which of the following radioactive isotopes were utilised for labelling protein and DNA in transduction experiment respectively?

  • a)

  • b)

  • c)

  • d) None of these

Answer:

 

Question: Dominance of RNA world is proved by

  • a) Splicing
  • b) Polyadenylation
  • c) All of these
  • d) Capping

Answer: Splicing

 

Question: Which plant was used by Taylor to prove semiconservative replication at chromosomal level?

  • a) Vicia faba
  • b) Trillium
  • c) Ophioglossum
  • d) Haematoxylon

Answer: Vicia faba

 

Question: Unwinding of DNA creates tension which is released by enzyme

  • a) Topoisomerase
  • b) Primase
  • c) Ligase
  • d) Helicase

Answer: Topoisomerase

 

Question: During polymerisation of deoxyribonucleosides triphosphates in bacteria which of the following enzyme is mainly required?

  • a) DNA dependent DNA polymerase
  • b) DNA gyrase
  • c) DNA dependent RNA polymerase
  • d) RNA dependent DNA polymerase

Answer: DNA dependent DNA polymerase

 

Question: DNA polymerases catalyse polymerisation of / in

  • a)

  • b)

  • c) Deoxyribonucleosides
  • d) Ribonucleotides

Answer: 

 

Question: During DNA replication which of the following does not act as substrates?

  • a) dUTP
  • b) dGTP
  • c) dCTP
  • d) dATP

Answer: dUTP

 

Question: Out of the two strands of DNA one is carrying genetic information for transcription and it is called

  • a) Template strand
  • b) Sense strand
  • c) Non template strand
  • d) Coding strand

Answer:  Template strand

 

Question: When a mature mRNA was hybridised to its gene certain loops were observed. These loops represent

  • a) Introns in DNA
  • b) Introns in rRNA
  • c) Exons in DNA
  • d) Exons in tRNA

Answer: Introns in DNA

 

Question: Poly A tail is present in

  • a) mRNA of eukaryotes
  • b) Promotor of bacteria
  • c) tRNA of eukaryotes
  • d) mRNA of bacteria

Answer:  mRNA of eukaryotes

 

Question: Find out the incorrect match

  • a) UAG – Sense codon
  • b) UGG – Tryptophan
  • c) UUU – Phenylalanine
  • d) GUG – Valine

Answer: UAG – Sense codon

 

Question: One codon codes for only one amino acid, hence the code is

  • a) Unambiguous and specific
  • b) Unambiguous and non-specific
  • c) Ambiguous and non-specific
  • d) Ambiguous and specific

Answer: Unambiguous and specific

 

Question: What is incorrect for UTR?

  • a) Present in between the translational unit in mRNA
  • b) Required for efficient translation process
  • c) Not recognised by any tRNA
  • d) Provide stability to mRNA

Answer:  Present in between the translational unit in mRNA

 

Question: In bacteria, catalytic RNA is found in

  • a) 50S subunit of ribosome
  • b) 40S subunit of ribosome
  • c) 60S subunit of ribosome
  • d) 30S subunit of ribosome

Answer: 50S subunit of ribosome

 

Question: In lac operon, the regulator gene codes for

  • a) Active repressor
  • b) Inactive repressor
  • c) Corepressor
  • d) Aporepressor

Answer: Active repressor

 

Question: Mark the incorrect option w.r.t. lac operon

  • a) Shows feed back repression
  • b) Is under positive as well as negative control
  • c) Controls catabolic pathway
  • d) Discovered by Jacob and Monod

Answer: Shows feed back repression

 

Question: In lac operon, the lac mRNA

  • a) Has several initiation and termination codons
  • b) Is not transcribed in the presence of lactose
  • c) Forms four different enzymes
  • d) Is involved in an anabolic reaction

Answer:  Has several initiation and termination codons

 

Question:  How many locations have been identified in human genome where single base differences occur?

  • a) 1.4 million
  • b) 14 million
  • c) 1.4 billion
  • d) 14 billion

Answer: 1.4 million

 

Question: The non-human model organisms sequenced in Human Genome project were

  • a) A nematode and fruit fly
  • b) Fish and birds
  • c) Wheat and rice
  • d) Garden pea and fruit fly

Answer: A nematode and fruit fly

 

Question: Mark the correct one (w.r.t. application of DNA fingerprinting)

  • a) More than one option is correct
  • b) Determining the population diversity
  • c) Forensic science
  • d) Determining the genetic diversity

Answer: More than one option is correct

 

Question: What is incorrect for human chromosome 1?

  • a) Its sequence was completed in May 2007
  • b) It was the last chromosome to be sequenced
  • c) It is one of the largest chromosome
  • d) It has maximum number of genes

Answer:  Its sequence was completed in May 2007

 

More Questions.......................................

 

Question: In the technique of DNA fingerprinting digestion of DNA is followed by

  • a) Electrophoresis
  • b) Hybridisation
  • c) Denaturation
  • d) Southern blotting

Answer: Electrophoresis

 

Question: In eukaryotes, RNA polymerase III catalyses the synthesis of

  • a) 5 S rRNA, tRNA & SnRNA
  • b) 28 S rRNA, 18 S rRNA & 5 S rRNA
  • c) All types of rRNA & tRNA
  • d) 28 S rRNA, 18 S rRNA & 5 S rRNA

Answer: 5 S rRNA, tRNA & SnRNA

 

Question:  Read the following statements:

A. Variation at genetic level arises due to mutations.
B. Technique of DNA fingerprinting was initially developed by Alec Jeffreys

  • a) Both (A) and (B) are correct
  • b) Both (A) and (B) are incorrect
  • c) Only (B) is correct
  • d) Only (A) is correct

Answer: Both (A) and (B) are correct

 

Question: In DNA fingerprinting, detection of hybridised DNA fragments is possible by

  • a) Autoradiography
  • b) Centrifugation
  • c) Blotting
  • d) Electrophoresis

Answer: Autoradiography

 

Question: Mark the correct match

  • a) VNTR – Intron
  • b) Sanger method – Determination of amino acid sequences in proteins only
  • c) Val operon – Found in eukaryotes
  • d) None of these

Answer:   VNTR – Intron

 

Question:

  • a) C G A T G C A T
  • b) A T G C A T C G
  • c) A T C G T A C G
  • d) T A C G T A G C

Answer: C G A T G C A T

 

Question: NHC structural proteins are

  • a) Required for packaging of chromatin at higher levels
  • b) Catalytic proteins rich in tryptophan and arginine
  • c) Regulatory proteins
  • d) Basic proteins rich in lysine, arginine

Answer: Required for packaging of chromatin at higher levels

 

Question: How many types of DNA polymerases are present in bacteria?

  • a) Three
  • b) Two
  • c) One
  • d) Five

Answer: Three

  

Question: Synthesis of leading and lagging strand require

  • a) Single and many primers respectively
  • b) Many primers
  • c) Single primer
  • d) Many and single primers respectively

Answer: Single and many primers respectively

 

Question: For the strand separation and stabilisation during DNA replication which of the following set of enzymes and proteins are required?

  • a) Topoisomerase, helicase, SSBP
  • b) Topoisomerase, helicase, ligase
  • c) SSBP, gyrase, primase
  • d)  SSBP, gyrase, primase

Answer: Topoisomerase, helicase, SSBP

 

Question: In eukaryotes, the RNA polymerase that synthesises tRNA is RNA polymerase ______ and is also responsible for formation of ______ rRNA.

  • a) III, 5 S
  • b) II, 18 S
  • c) I, 5 S
  • d) II, 5.8 S

Answer: III, 5 S

 

Question: What is correct for bacterial transcription?

  • a) Transcription and translation takes place in the same compartment
  • b) Translation can begin when mRNA is fully transcribed
  • c) mRNA requires processing to become active
  • d) Rho factor initiates the process

Answer:  Transcription and translation takes place in the same compartment

 

Question: Which of the following is not required during post transcriptional processing in eukaryotes?

  • a) ScRNA
  • b) Methyl guanosine triphosphate
  • c)  Ligase
  • d) SnRNA

Answer: ScRNA

 

Question: Which of the following feature is correct for bacteria?

  • a) DNA can be chromosomal as well as extrachromosomal
  • b) Linear ss-DNA representing single chromosome
  • c) DNA does not show coiling
  • d) Presence of intervening sequences in DNA

Answer: DNA can be chromosomal as well as extrachromosomal

 

Question: In-vitro template independent RNA synthesis is a feature of

  • a) Ochoa enzyme
  • b) DNA polymerase
  • c) Reverse transcriptase
  • d) RNA polymerase

Answer: Ochoa enzyme

 

Question: In protein synthesis, which of the following are required for the synthesis of charged tRNA?

  • a) Amino acid, ATP, Mg++, enzyme, tRNA
  • b) Amino acid, GTP, initiation codon, ribosome
  • c) Amino acid, ATP, K+, enzyme, mRNA
  • d) Aminoacyl tRNA, ribosome, initiation codon, release factor

Answer: Amino acid, ATP, Mg++, enzyme, tRNA

 

Question: Termination of polypeptide synthesis in bacteria differs from eukaryotes in

  • a) Involving more than one type of release factors
  • b) Having different termination codons
  • c) Being GTP dependent
  • d) All of these

Answer: Involving more than one type of release factors

 

Question: The accessibility of promoter regions of bacterial DNA in many cases regulated by the interaction of proteins with sequences termed

  • a) Operators
  • b) Inhibitor genes
  • c) Structural genes
  • d) Regulators

Answer: Operators

 

Question: When the genomes of two people are cut using the same restriction enzyme, the length and number of fragments obtained are different, this is called

  • a) RFLP
  • b) PCR
  • c) EST
  • d) Northern blotting

Answer:  RFLP

 

Question: Which of the following does not code for any proteins?

  • a) More than one option is correct
  • b) Mini-satellites
  • c) Exons
  • d) Micro-satellites

Answer: More than one option is correct

 

Question: Which statement is correct for homeotic genes?

  • a) Control is exerted through homeodomain proteins
  • b) Mutation in these genes not results in conversion of one body part into another
  • c) Such genes have been studied extensively in humans
  • d) Control oncogenesis process

Answer: Control is exerted through homeodomain proteins

 

Question: In which step of DNA profiling, nitrocellulose membrane is used?

  • a) Blotting
  • b) DNA amplification
  • c) Autoradiography
  • d) Denaturation

Answer:  Blotting

 

Question: Repressor of lac-operon

  • a) Is a tetrameric protein
  • b) Has only one side
  • c) Having a molecular weight of 16,000
  • d) Is made by operator gene

Answer: Is a tetrameric protein

 

Question: Select the correct one (w.r.t. Wobble hypothesis)

  • a) Third base can establish H-bonds even with the non complementary anticodon
  • b) Third base of a codon lacks vibrating capacity
  • c) Specificity of a anticodon is particularly determined by first two codon
  • d) Major cause of degeneracy is the first two N-bases of codon

Answer: Third base can establish H-bonds even with the non complementary anticodon

 

Question: A set of genes or cDNA is immobilized on a glass slide and used in transcriptome studies is called

  • a) Microarray
  • b) DNA chip
  • c) Genome
  • d) Proteome

Answer: Microarray

 

Question:  Which of the following bond is not present in DNA?

  • a)

  • b)

  • c)

  • d)

Answer:

 

Question: If there are 81 million bases in RNA of human cell, then calculate the total number of introns present in cDNA

  • a) Zero
  • b) Half the number of ribonucleotides
  • c)  Equal to ribonucleotides
  • d) 27 millions

Answer: Zero

 

Question: Splicing is necessary for preparing a mature transcript and its movement to cytoplasm. It requires

  • a) snRNA and proteins
  • b) scRNA and snRNA
  • c) scRNA only
  • d) scRNA and proteins

Answer:  snRNA and proteins

 

Question:

  • a) Ribosomal binding loop
  • b) AA - tRNA synthetase binding loop
  • c) Nodoc site
  • d) None of these

Answer:  Ribosomal binding loop

 

Question:

  • a) Two amino acids
  • b) Three amino acids
  • c) Six amino acids
  • d) Five amino acids

Answer: Two amino acids

 

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