CBSE Class 11 Biology Excretory Products And Their Elimination Worksheet Set C

Excretory Products And Their Elimination MCQ Questions with Answers Class 11 Biology

Question- A fall in glomerular filtration rate (GFR) activates 

(1) Posterior pituitary to release vasopressin

(2) Juxtra glomerular cells to release renin

(3) Adrenal cortex to release aldosterone

(4) Adrenal medulla to release adrenaline

Answer (2)

Question- In response to decrease in blood volume and blood pressure which of the following do not occur?

(1) Secretion of renin

(2) Secretion of aldosterone

(3) Secretion of vassopressin

(4) Secretion of ANF

Answer (4)

Question- Uricotelic mode of passing out nitrogenous wastes is found in 

(1) Insects and Amphibians

(2) Reptiles and Birds

(3) Birds and Annelids

(4) Amphibians and Reptiles

Answer (2)

Question- Angiotensinogen is a protein produced and secreted by 

(1) Macula densa cells

(2) Endothelial cells (cells lining the blood vessels)

(3) Liver cells

(4) Juxtaglomerular (JG) cells

Answer (3)

Question- Which of the following changes can occur in response to increased Angiotensin-II level?

(1) Increase in the glomerular hydrostatic pressure (GHP)

(2) Inhibition of aldosterone

(3) Decrease in the GFR

(4) Decrease in BCOP

Answer (1)

Question- The net p ressure gradient that causes the fluid to filter out of the glomeruli into the capsule is

(1) 20 mm Hg

(2) 75 mm Hg

(3) 30 mm Hg

(4) 50 mm Hg

Answer (1)

Question- Contractile vacuole to pump out excess of water is found in

(1) Fresh water protozoans

(2) Marine protozoans

(3) Parasitic protozoans

(4) Lower chordates

Answer (1)

Question- Which one of the following correctly explains the function of a specific part of a human nephron?

(1) Afferent arteriole: carries the blood away from the glomerulus towards renal vein.

(2) Podocytes: Create minute spaces (slit pores) for the filtration of blood into the Bowman's capsule.

(3) Henle's loop: most reabsorption of the major substances from the glomerular filtrate

(4) Distal convoluted tubule: reabsorption of K+ ions into the surrounding blood capillaries

Answer (2)

Question- In Ornithine cycle, which of the following wastes are removed from the blood? [AIPMT (Prelims)-2005]

(1) Urea and urine

(2) Ammonia and urea

(3) CO₂and ammonia

(4) CO₂ and urea

Answer (3)

Question- Which of the following statement is not true?

(1) Descending limb of loop of Henle is permeable to urea

(2) DCT functions in K+, Na+ homeostasis

(3) Descending limb is impermeable to water

(4) Loop of Henle is largely responsible for concentrating urine

Answer (3)

Question- Two animals in which the nitrogenous wastes are excreted from body in the form of uric acid are

(1) Birds and lizards

(2) Frogs and cartilaginous fishes

(3) Insects and bony fishes

(4) Mammals and mollusc

Answer (1)

Question- Uricotelism is found in

(1) Mammals and birds

(2) Fishes and fresh water protozoans

(3) Birds, reptiles and insects

(4) Frogs and toads

Answer (3)

Question- Which one of the following is not a part of a renal pyramid?

(1) Loops of Henle

(2) Peritubular capillaries

(3) Convoluted tubules

(4) Collecting ducts

Answer (3)

Question- A terrestrial animal must be able to

(1) Excrete large amount of water in urine

(2) Conserve water

(3) Actively pump salts out through the skin

(4) Excrete large amounts of salts in urine

Answer (2)

Question- Concentration of urine depends upon which of the following?

(1) Bowman’s capsule

(2) Length of Henle’s loop

(3) PCT

(4) Network of capillaries arising from glomerulus

Answer (2)

Question- Which one of the following statements in regard to the excretion by the human kidneys is correct?

(1) Ascending limb of Loop of Henle is impermeable to electrolytes

(2) Descending limb of Loop of Henle is impermeable to water

(3) Distal convoluted tubule is incapable of reabsorbing HCO₃

(4) Nearly 99 percent of the glomerular filtrate is reabsorbed by the renal tubules

 Answer (4)

Question- A person is undergoing prolonged fasting. His urine will be found to contain abnormal quantities of:

(1) Fats

(2) Ketones

(3) Amino acids

(4) Glucose

Answer (2)

Question- Which one is mainly responsible for absorption of Na+ in the PCT part of nephron?

(1) Angiotensin-II

(2) Angiotensin-I

(3) Aldosterone

(4) Atrial Natriuretic Factor (ANF)

Answer (1)

Question- Uric acid is the chief nitrogenous component of the excretory products of

(1) Frog

(2) Man

(3) Earthworm

(4) Cockroach

Answer (4)

Question- A condition of failure-of kidney to form urine is called

(1) Anuria

(2) Deamination

(3) Entropy

(4) Uraemia

Answer (1)

Question- In ureotelic animals, urea is formed by

(1) Kreb’s cycle

(2) EM pathway

(3) Ornithine cycle

(4) Cori’s cycle

Answer (3)

Question- What will happen if the stretch receptors of the urinary bladder wall are totally removed ?

(1) Micturition will continue

(2) Urine will continue to collect normally in the bladder

(3) There will be no micturition

(4) Urine will not collect in the bladder

Answer (3)

Question- Uric acid is produced by metabolism of

(1) Adenine

(2) Guanine

(3) Cytosine

(4) Both (1) & (2)

Answer (4)

Question-  Which one of the following statements is correct with respect to kidney function regulation?

(1) During summer when body loses lot of water by evaporation, the release of ADH is suppressed

(2) When someone drinks lot of water, ADH release is suppressed

(3) Exposure to cold temperature stimulates ADH release

(4) An increase in glomerular blood flow stimulates formation of Angiotensin II

 Answer (2)

Question- Which out of the four parts mentioned below does not constitute a part of single uriniferous tubule?

(1) Distal convoluted tubule

(2) Collecting duct

(3) Bowman’s capsule

(4) Loop of Henle

Answer (2)

Question-  Brush border surface is the distinct feature of which of the following part of nephron?

(1) PCT

(2) Ascending limb of loop of Henle

(3) DCT

(4) Collecting duct

Answer (1)

Question- The principal nitrogenous excretory compound in humans is synthesised 

(1) In the liver, but eliminated mostly through kidneys

(2) In kidneys, but eliminated mostly through liver

(3) In kidneys as well as eliminated by kidneys

(4) In liver and also eliminated by the same through bile

Answer (1)

Question- Hypertonicity of filtrate is minimum at

(1) Base of loop of henle

(2) Inner most part of medulla

(3) Outer part of medulla

(4) Cortical region

Answer (4)

Question- If Henle’s loop were absent from mammalian nephron, which of the following is to be expected ?

(1) There will be no urine formation

(2) There will be hardly any change in the quality and quantity of urine formed

(3) The urine will be more concentrated

(4) The urine will be more dilute

Answer (4)

Question-  If an osmoconformer animal is placed in sea water then

(1) It will develop ionocytes to actively absorb the salts from outside

(2) It will develop a thick body cover to prevent entry of excess of water

(3) It will start passing diluted urine

(4) It will change osmolarity of its body fluid

Answer (4)

Question- Which of the following is not a feature of cortical nephrons?

(1) These are more common, approximately 85% of nephrons

(2) Their glomeruli are in outer cortex

(3) Their loop of Henle extend to a short distance into the medulla

(4) They are associated with vasa recta

Answer (4)

More Question

Q1. What are three main forms in which animals excrete nitrogenous wastes?

Q2. What is ammonotelism, ureotelism & uricotelism? Give advantages of ureotelism & uricotelism.

Q3. Why tadpoles are ammotetic whereas frogs are ureotelic?

Q4. Describe protonephridia & give examples of animals in which they are found.

Q5. Describe structure of metanephridia, malphigian tubules & green glands with examples.

Q6. Draw labeled diagrams of Human Urinary system, L.S. of Human Kidney & explain its structure.

Q7. What are two type of nephrons based on their position in kidney. Give differences between them.

Q8. What are three processes involved in urine formation?

Q9. Describe the role of different regions of nephrons in urine formation.

Q10. How much is the filtering force required in the glomeruli? What is the nature of filtrate of PCT?

Q11. Both thin & thick segments of ascending loops of Henle transport Nacl into intestinal fluid. What is the difference in their respective mode of transport?

Q12. What difference in observed in ascending & descending limbs of Henle’s loop with reference to permeability of water?

Q13. What is counter current mechanism? Where does it operate & what is its use?

Q14. What is the role of the following in regulation of Kidney function:- (i) Hypothalamus (ii) JGA (iii) ANF

Q15. What is micturition? Explain

Q16. What is the role of lungs, liver and skin in excretion?

Q17. Name 3 disorders of kidney.

Q18. Define haemodialysis, Explain technique.

Q19. Under which condition is kidney transplant required.
 

1. Ammonia, urea and uric acid →
o the major forms of nitrogenous wastes excreted by the animals.
o Ammonia →
• most toxic form
• The process of excreting ammonia is AMMONOTELISM
• e.g. Many bony fishes, aquatic amphibians and aquatic insects
• Ammonia, as it is readily soluble
• Generally excreted by diffusion across body surfaces or through gill surfaces (in fish) as ammonium ions.
• Kidneys do not play any significant role in its removal.
o Uric acid
• least toxic,
• can be removed with a minimum loss of water
• in the form of pellet or paste
• Terrestrial adaptation for water conservation

• URICOTELIC ANIMALS
• Reptiles, birds, land snails and insects
o Urea
• Terrestrial adaptation for conservation of water.
• UREOTELIC ANIMALS
• Mammals, many terrestrial amphibians and MARINE FISHES
• AMMONIA IS CONVERTED INTO UREA IN THE LIVER
• Urea released into the blood which is filtered and excreted out by the kidneys.
• Some amount of urea may be retained in the kidney matrix of some of these animals to maintain a desired osmolarity.

2. EXCRETORY STRUCTURES.
o In most of the invertebrates, → simple tubular structures
o Vertebrates have complex tubular organs called kidneys.

o PROTONEPHRIDIA OR FLAME CELLS →
• in Platyhelminthes (Flatworms, e.g., Planaria),
• rotifers,
• some annelids and
• the cephalochordate – Amphioxus.
• Protonephridia are primarily concerned with ionic and fluid volume regulation, i.e., osmoregulation.

o NEPHRIDIA →
• Tubular excretory structures
• Present in earthworms and other annelids.
• Help to remove nitrogenous wastes and maintain a fluid and ionic balance.

o MALPIGHIAN TUBULES →
• excretory structures of most of the insects including cockroaches.
• Help in the removal of nitrogenous wastes and osmoregulation.
o ANTENNAL GLANDS / GREEN GLANDS→
• perform the excretory function in crustaceans like prawns.

3. HUMAN EXCRETORY SYSTEM
o Consists of a pair of kidneys, one pair of ureters, a urinary bladder and a urethra.
o KIDNEYS are reddish brown, bean shaped structures situated between the levels of last thoracic and third lumbar vertebra close to the dorsal inner wall of the abdominal cavity.
o Each kidney of an adult human measures 10-12 cm in length, 5-7 cm in width, 2-3 cm in thickness with an average weight of 120- 170 g.
o Towards the centre of the inner concave surface of the kidney is a notch called HILUM THROUGH WHICH URETER, BLOOD VESSELS AND NERVES ENTER.
o Inner to the hilum is a broad funnel shaped space called the RENAL PELVIS with projections called CALYCES.
o The outer layer of kidney is a tough capsule.
o Inside the kidney, there are two zones,
• an outer cortex and
• an inner medulla.
o The medulla is divided into a few conical masses (medullary pyramids) projecting into the calyces (sing.: calyx).
o The cortex extends in between the medullary pyramids as renal columns called COLUMNS OF BERTINI
o Each kidney has nearly one million complex tubular structures called

NEPHRONS, which are THE FUNCTIONAL UNITS.
o Each nephron has two parts – the glomerulus and the renal tubule.
o GLOMERULUS IS A TUFT OF CAPILLARIES formed by the afferent arteriole – a fine branch of renal artery.
o Blood from the glomerulus is carried away by an EFFERENT ARTERIOLE.
o The renal tubule begins with a double walled cup-like structure called Bowman’s capsule, which encloses the glomerulus.
o Glomerulus along with Bowman’s capsule, is called the MALPIGHIAN BODY or RENAL CORPUSCLE
o The tubule continues further to form a highly coiled network – proximal convoluted tubule (PCT).
o A HAIRPIN SHAPED HENLE’S LOOP is the next part of the tubule which has a descending and an ascending limb.
o The ascending limb continues as another highly coiled tubular region called distal convoluted tubule (DCT).
o The DCTs of many nephrons open into a straight tube called COLLECTING DUCT, many of which converge and open into the renal pelvis through medullary pyramids in the calyces.
o The Malpighian corpuscle, PCT and DCT of the nephron are situated in the cortical region of the kidney whereas the loop of Henle dips into the medulla.
o In majority of nephrons, the loop of Henle is too short and extends only very little into the medulla. Such nephrons are called CORTICAL NEPHRONS.
o In some of the nephrons, the loop of Henle is very long and runs deep into the medulla. These nephrons are called JUXTA MEDULLARY NEPHRONS.
o The efferent arteriole emerging from the glomerulus forms a fine capillary network around the renal tubule called the PERITUBULAR CAPILLARIES.
o A minute vessel of this network runs parallel to the Henle’s loop forming a ‘U’ shaped VASA RECTA.
o Vasa recta is absent or highly reduced in cortical nephrons.
4. URINE FORMATION
5. Urine formation involves three main processes namely, that takes place in different parts of the nephron
o glomerular filtration,
o reabsorption and
o secretion

6. The first step in urine formation is the filtration of blood, which is carried out by the glomerulus and is called GLOMERULAR FILTRATION.

7. On an average, 1100-1200 ml of blood is filtered by the kidneys per minute which constitute roughly 1/5th of the blood pumped out by each ventricle of the heart in a minute.

8. The glomerular capillary blood pressure causes filtration of blood through 3 layers,
i.e., the endothelium of glomerular blood vessels, the epithelium of Bowman’s capsule and a basement membrane between these two layers.

9. The epithelial cells of Bowman’s capsule called PODOCYTES are arranged in an intricate manner so as to leave some minute spaces called FILTRATION SLITS OR SLIT PORES.

10. Blood is filtered so finely through these membranes, that almost all the constituents of the plasma except the proteins pass onto the lumen of the Bowman’s capsule.
Therefore, it is considered as a PROCESS OF ULTRA FILTRATION.

11. The amount of the filtrate formed by the kidneys per minute is called glomerular filtration rate (GFR).

12. GFR in a healthy individual is approximately 125 ml/minute, i.e., 180 litres per day !

13. The kidneys have built-in mechanisms for the regulation of glomerular filtration rate.

14. JUXTA GLOMERULAR APPARATUS (JGA) →
o SPECIAL SENSITIVE REGION formed by cellular modifications in the distal convoluted tubule and the afferent arteriole at the location of their contact.
o A fall in GFR can activate the JG CELLS TO RELEASE RENIN which can stimulate the glomerular blood flow and thereby the GFR back to normal.
o A comparison of the volume of the filtrate formed per day (180 litres per day) with that of the urine released (1.5 litres), suggest that nearly 99 per cent of the filtrate has to be reabsorbed by the renal tubules.
o This process is called REABSORPTION.
o The tubular epithelial cells in different segments of nephron perform this either by active or passive mechanisms.
o For example, SUBSTANCES LIKE GLUCOSE, AMINO ACIDS, NA+ , ETC., IN THE FILTRATE ARE REABSORBED ACTIVELY whereas the NITROGENOUS WASTES ARE ABSORBED BY PASSIVE TRANSPORT.
o Reabsorption of water also occurs passively in the initial segments of the nephron.
o During urine formation, the tubular cells secrete substances like H+ , K + and ammonia into the filtrate.
o Tubular secretion is also an important step in urine formation as it helps in the maintenance of ionic and acid base balance of body fluids.

15. FUNCTION OF THE TUBULES
o PROXIMAL CONVOLUTED TUBULE (PCT):
• Lined by simple cuboidal brush border epithelium which increases the surface area for reabsorption.
• Nearly all of the essential nutrients, and 70-80 per cent of electrolytes and water are reabsorbed by this segment.
• Helps to maintain the pH and ionic balance of the body fluids
• selective secretion of hydrogen ions, ammonia and potassium ions into the filtrate and by absorption of HCO3 – from it.

o HENLE’S LOOP:
• Reabsorption is minimum in its ascending limb.
• this region plays a significant role in the maintenance of high osmolarity of medullary interstitial fluid.
• The descending limb of loop of Henle is permeable to water but almost impermeable to electrolytes.
• This concentrates the filtrate as it moves down.
• The ascending limb is impermeable to water but allows transport of electrolytes actively or passively.
• Therefore, as the concentrated filtrate pass upward, it gets diluted due to the passage of electrolytes to the medullary fluid.
o Distal Convoluted Tubule (DCT):
• Conditional reabsorption of Na+ and water takes place in this segment.
• DCT is also capable of reabsorption of HCO3 – and selective secretion of hydrogen and potassium ions and NH3 to maintain the pH and sodium-potassium balance in blood.
o Collecting Duct:
• This long duct extends from the cortex of the kidney to the inner parts of the medulla.
• Large amounts of water could be reabsorbed from this region to produce a concentrated urine.
• This segment allows passage of small amounts of urea into the medullary interstitium to keep up the osmolarity.
• It also plays a role in the maintenance of pH and ionic balance of blood by the selective secretion of H+ and K+ ions

16. MECHANISM OF CONCENTRATION OF THE FILTRATE
o Mammals have the ability to produce a concentrated urine.
o THE HENLE’S LOOP AND VASA RECTA PLAY A SIGNIFICANT ROLE
o The flow of filtrate in the two limbs of Henle’s loop is in opposite directions and thus forms a COUNTER CURRENT. 
o The flow of blood through the two limbs of vasa recta is also in a counter current pattern.
o The proximity between the Henle’s loop and vasa recta, as well as the counter current in them help in maintaining an increasing osmolarity towards the inner medullary interstitium, i.e., from 300 mOsmolL–1 in the cortex to about 1200 mOsmolL–1 in the inner medulla.
o THIS GRADIENT IS MAINLY CAUSED BY NaCl AND UREA.
o NaCl is transported by the ascending limb of Henle’s loop which is exchanged with the descending limb of vasa recta.
o NaCl is returned to the interstitium by the ascending portion of vasa recta.
o Similarly, small amounts of urea enter the thin segment of the ascending limb
of Henle’s loop which is transported back to the interstitium by the collecting tubule.
o THE ABOVE DESCRIBED TRANSPORT OF SUBSTANCES FACILITATED BY THE SPECIAL ARRANGEMENT OF HENLE’S LOOP AND VASA RECTA IS CALLED THE COUNTER CURRENT MECHANISM
o This mechanism helps to maintain a concentration gradient in the medullary interstitium.
o Presence of such interstitial gradient helps in an easy passage of water from the collecting tubule thereby concentrating the filtrate (urine).
o Human kidneys can produce urine nearly four times concentrated than the initial filtrate formed.

17. REGULATION OF KIDNEY FUNCTION
o The functioning of the kidneys is efficiently monitored and regulated by hormonal feedback mechanisms involving
• the hypothalamus,
• JGA and
• The heart.

o OSMORECEPTORS in the body are ACTIVATED BY →
• changes in blood volume,
• body fluid volume and
• ionic concentration.
o An excessive loss of fluid from the body can activate these receptors which stimulate the hypothalamus to release antidiuretic hormone (ADH) or vasopressin from the neurohypophysis.
o ADH facilitates water reabsorption from latter parts of the tubule, thereby preventing diuresis.
o An increase in body fluid volume can switch off the osmoreceptors and suppress the ADH release to complete the feedback.
o ADH can also affect the kidney function by its constrictory effects on blood vessels.
o THIS CAUSES AN INCREASE IN BLOOD PRESSURE.
o An increase in blood pressure can increase the glomerular blood flow and 
thereby the GFR.

o THE JGA PLAYS A COMPLEX REGULATORY ROLE.
o A fall in glomerular blood flow/glomerular blood pressure/GFR can activate the JG cells to release renin which converts angiotensinogen in blood to angiotensin I and further to angiotensin II.
o ANGIOTENSIN II, BEING A POWERFUL VASOCONSTRICTOR, increases the glomerular blood pressure and thereby GFR.
o Angiotensin II also activates the adrenal cortex to release Aldosterone.
o Aldosterone causes reabsorption of Na+ and water from the distal parts of the tubule.
o This also leads to an increase in blood pressure and GFR.
o This complex mechanism is generally known as the Renin-Angiotensin mechanism.
o An increase in blood flow to the atria of the heart can cause the release of Atrial Natriuretic Factor (ANF).
o ANF can cause vasodilation (dilation of blood vessels) and thereby decrease the blood pressure.
o ANF mechanism, therefore, acts as a check on the renin-angiotensin mechanism.

18. MICTURITION
o Urine formed by the nephrons is ultimately carried to the urinary bladder where it is stored till a voluntary signal is given by the central nervous system (CNS).
o This signal is initiated by the stretching of the urinary bladder as it gets filled with urine.
o In response, the STRETCH RECEPTORS ON THE WALLS OF THE BLADDER send signals to the CNS.
o The CNS passes on motor messages to initiate the contraction of smooth muscles of the bladder and simultaneous relaxation of the urethral sphincter causing the release of urine.
o The process of release of urine is called MICTURITION
o The neural mechanisms causing it is called the MICTURITION REFLEX.
o An adult human excretes, on an average, 1 to 1.5 litres of urine per day.
o The urine formed is a light yellow coloured watery fluid which is slightly acidic (pH-6.0) and has a characteristic odour.
o On an average, 25-30 gm of urea is excreted out per day.
o Various conditions can affect the characteristics of urine.
o Analysis of urine helps in clinical diagnosis of many metabolic discorders as well as malfunctioning of the kidney.
• For example, presence of glucose (Glycosuria) and ketone bodies (Ketonuria) in urine are indicative of diabetes mellitus.

19. ROLE OF OTHER ORGANS IN EXCRETION
o Other than the kidneys, lungs, liver and skin also help in the elimination of excretory wastes.
o Our lungs remove large amounts of CO2 (approximately 200mL/ minute) and also significant quantities of water every day.
o LIVER, THE LARGEST GLAND IN OUR BODY, secretes bile-containing substances like bilirubin, biliverdin, cholesterol, degraded steroid hormones, vitamins and drugs.
o Most of these substances ultimately pass out along with digestive wastes.
o The sweat and sebaceous glands in the skin can eliminate certain substances through their secretions.
o Sweat produced by the sweat glands is a watery fluid containing NaCl, small amounts of urea, lactic acid, etc.
o Primary function of sweat is to facilitate a cooling effect on the body surface, it also helps in the removal of some of the wastes mentioned above.
o Sebaceous glands eliminate certain substances like sterols, hydrocarbons and waxes through sebum.
o This secretion provides a protective oily covering for the skin.

20. DISORDERS OF THE EXCRETORY SYSTEM
o Malfunctioning of kidneys can lead to ACCUMULATION OF UREA IN BLOOD, A CONDITION CALLED UREMIA, which is highly harmful and may LEAD TO KIDNEY FAILURE. In such patients, urea can be removed by a process called HEMODIALYSIS.
o Kidney transplantation is the ultimate method in the correction of acute renal failures (kidney failure).
o A functioning kidney is used in transplantation from a donor, preferably a close relative, to minimise its chances of rejection by the immune system of the host.
o Modern clinical procedures have increased the success rate of such a complicated technique.
o Renal calculi: Stone or insoluble mass of crystallised salts (oxalates, etc.) formed within the kidney.
o Glomerulonephritis: Inflammation of glomeruli of kidney

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